Marije I Koenders Selected Research

Experimental Arthritis

1/2022	Local inhibition of TGF-β1 signaling improves Th17/Treg balance but not joint pathology during experimental arthritis.
11/2021	Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development.
1/2021	Systemic overexpression of interleukin-22 induces the negative immune-regulator SOCS3 and potently reduces experimental arthritis in mice.
1/2021	'SMASH' recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models.
12/2020	Targeted photodynamic therapy selectively kills activated fibroblasts in experimental arthritis.
1/2019	Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study.
1/2019	Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice.
12/2018	Microbiota-Dependent Involvement of Th17 Cells in Murine Models of Inflammatory Arthritis.
1/2018	Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models.
1/2018	Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis.

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Marije I Koenders Research Topics

Disease

59	Arthritis (Polyarthritis) 11/2021 - 02/2004
36	Inflammation (Inflammations) 01/2022 - 12/2003
32	Rheumatoid Arthritis 01/2022 - 12/2003
29	Experimental Arthritis 01/2022 - 02/2004
8	Osteoarthritis 01/2019 - 07/2015
7	Autoimmune Diseases (Autoimmune Disease) 09/2019 - 10/2011
4	Disease Progression 10/2017 - 02/2004
3	Necrosis 01/2021 - 08/2011
3	Pain (Aches) 01/2021 - 01/2016
3	Gouty Arthritis 01/2018 - 11/2010
2	Periodontitis 09/2019 - 05/2014
2	Osteitis 01/2019 - 10/2016
2	Hyperplasia 01/2019 - 10/2010
2	Gout 01/2018 - 01/2016
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2017 - 01/2016
2	Joint Diseases (Joint Disease) 10/2016 - 12/2003
2	Synovitis 11/2015 - 10/2005
2	Mycoses (Diseases, Fungus) 07/2015 - 10/2013
1	Hypertrophy 01/2022
1	Systemic Scleroderma (Systemic Sclerosis) 11/2021
1	Hypercholesterolemia 11/2019
1	Edema (Dropsy) 01/2018

Drug/Important Bio-Agent (IBA)

24	CytokinesIBA 09/2019 - 02/2004
21	Interleukin-17 (Interleukin 17)IBA 12/2018 - 02/2004
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2015
10	Interleukin-1 (Interleukin 1)IBA 01/2021 - 09/2004
10	AntigensIBA 12/2020 - 07/2005
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 09/2004
8	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2021 - 01/2008
6	InterleukinsIBA 01/2021 - 10/2010
6	Matrix Metalloproteinases (MMPs)IBA 11/2019 - 10/2005
6	LigandsIBA 01/2018 - 01/2008
6	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2015 - 12/2003
5	Interleukin-22 (IL-22)IBA 01/2021 - 10/2011
5	Messenger RNA (mRNA)IBA 01/2021 - 07/2005
5	Proteoglycans (Proteoglycan)IBA 01/2019 - 09/2004
5	Interleukin-6 (Interleukin 6)IBA 01/2018 - 06/2004
5	Toll-Like Receptor 2IBA 04/2014 - 12/2003
4	Antigen-Antibody Complex (Immune Complex)IBA 11/2019 - 11/2007
4	AntibodiesIBA 09/2019 - 06/2015
3	AlarminsIBA 01/2021 - 10/2016
3	Etanercept (Enbrel)FDA Link 01/2021 - 03/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 10/2016
3	AutoantibodiesIBA 01/2021 - 09/2015
3	InflammasomesIBA 01/2018 - 11/2010
3	Uric Acid (Urate)IBA 01/2018 - 11/2010
3	ElementsIBA 08/2017 - 01/2005
2	2- (5- benzo(1,3)dioxol- 5- yl- 2- tert- butyl- 3H- imidazol- 4- yl)- 6- methylpyridine hydrochlorideIBA 01/2022 - 01/2022
2	LuciferasesIBA 01/2022 - 01/2018
2	Transcription Factors (Transcription Factor)IBA 01/2022 - 08/2011
2	Liposomes (Liposome)IBA 11/2021 - 01/2017
2	OligosaccharidesIBA 01/2019 - 01/2019
2	Collagenases (Collagenase)FDA Link 01/2019 - 01/2018
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2018 - 06/2015
2	InterferonsIBA 12/2018 - 04/2014
2	c-Mer Tyrosine KinaseIBA 01/2018 - 01/2018
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 07/2015
2	ZymosanIBA 01/2018 - 06/2004
2	Therapeutic UsesIBA 01/2018 - 01/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2017 - 01/2017
2	interleukin-21 (interleukin 21)IBA 01/2017 - 04/2014
2	Interleukin-10 (Interleukin 10)IBA 03/2016 - 11/2015
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2016 - 11/2015
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2016 - 11/2010
2	Interleukin-23 (Interleukin 23)IBA 06/2015 - 01/2008
2	Myeloid Differentiation Factor 88IBA 06/2012 - 12/2003
2	Interleukin-17 ReceptorsIBA 08/2011 - 10/2005
2	Caspase 1 (ICE Protease)IBA 11/2010 - 12/2009
2	Interleukin-1beta (Interleukin 1 beta)IBA 12/2009 - 01/2008
1	tofacitinibIBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2021
1	NADPH Oxidase 2IBA 10/2021
1	pristane (pristan)IBA 01/2021
1	CollagenIBA 01/2021
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 01/2021
1	Pentetic Acid (DTPA)FDA LinkGeneric 12/2020
1	Apolipoproteins E (ApoE)IBA 11/2019
1	oxidized low density lipoproteinIBA 11/2019
1	ApolipoproteinsIBA 11/2019
1	Biological ProductsIBA 09/2019
1	PrebioticsIBA 01/2019
1	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 01/2019
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2019
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2019
1	JNK Mitogen-Activated Protein KinasesIBA 01/2018
1	Tartrate-Resistant Acid PhosphataseIBA 01/2018
1	Immunoglobulin M (IgM)IBA 01/2018
1	Peroxidase (Myeloperoxidase)IBA 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	Rheumatoid FactorIBA 01/2018
1	dapansutrileIBA 01/2018

Therapy/Procedure

10	Therapeutics 01/2018 - 12/2003
5	Intra-Articular Injections 01/2021 - 12/2008
4	Photochemotherapy (Photodynamic Therapy) 01/2022 - 12/2020
2	Aftercare (After-Treatment) 01/2017 - 01/2014
2	Intraperitoneal Injections 10/2013 - 05/2010
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 08/2017